Barrett's esophagus : emerging evidence for improved clinical practice / by D. Pleskow and T. Erim
This book: "is a comprehensive reference on the treatment and new imaging modalities of Barrett’s Esophagus for researchers, clinicians, and scholars. Each chapter is composed from the perspective of investigators who summarize the data as well as the reasoning behind why those studies were conceived.In addition, the future directions of research are discussed within each chapter, providing insights from the investigators. Research questions are described, and cutting-edge applications are explained. Each chapter contains clinical scenarios to highlight the directions in which the research is, and should be, heading.
- Provides a perspective into the research behind Barrett’s Esophagus
- Emphasizes the emerging technologies in surveillance and treatment of Barrett’s
- Features clinical scenarios to highlight the directions in which research is, and should be, heading" Provided by online publisher
This book "provides up-to-date information regarding the most effective diagnostic protocols and CMR sequences for the evaluation of patients with suspected or known ARVC/D. It includes CMR protocol summaries and clinical algorithms presented as flow diagrams, many of which have never been previously published. The book contains case reports from the practice and database of Dr. Frank I. Marcus, world renowned ARVC/D expert; as well as input from imaging experts from a large academic center with unique RV pathology imaging experience. This title is the perfect pocket companion for cardiologists, pediatric cardiologists, cardiac imaging and electrophysiology specialists as well as cardiology researchers.- The only comprehensive MRI reference focused and dedicated on the utilization of MRI in screening, diagnosis, therapeutic guidance and prognostic assessment of ARVC/D.
- Provides evidence based diagnostic and prognostic algorithms for management of patients with known and suspected ARVC/D.
- Contains concise clinical CMR acquisition protocol and evidence-based summaries of recommendations and multiple practical tips and tricks shared by experts in the field.
- Includes practical guidelines helping to determine pre-test and post-test likelihood of ARVC/D; as well as CMR evidence of the disease progression.
- Accompanying website provides complementary videos important for the understanding of ARVC diagnosis." Provided by online publisher
This book "contains operational procedures, policy considerations, and the many lessons learned by The Cancer Genome Atlas Project. This book guides the reader through methods in patient sample acquisition, the establishment of data generation and analysis pipelines, data storage and dissemination, quality control, auditing, and reporting.
This book is essential for those looking to set up or collaborate within a large-scale genomics research project. All authors are contributors to The Cancer Genome Atlas (TCGA) Program, a NIH- funded effort to generate a comprehensive catalog of genomic alterations in more than 35 cancer types.
As the cost of genomic sequencing is decreasing, more and more researchers are leveraging genomic data to inform the biology of disease. The amount of genomic data generated is growing exponentially, and protocols need to be established for the long-term storage, dissemination, and regulation of this data for research. The book's authors create a complete handbook on the management of research projects involving genomic data as learned through the evolution of the TCGA program, a project that was primarily carried out in the US, but whose impact and lessons learned can be applied to international audiences.
- Establishes a framework for managing large-scale genomic research projects involving multiple collaborators
- Describes lessons learned through TCGA to prepare for potential roadblocks
- Evaluates policy considerations that are needed to avoid pitfalls
- Recommends strategies to make project management more efficient" Provided by online publisher
This book "is a centralized, easy-access guide to preparing for cases most commonly encountered during training. Written by expert author teams consisting of both attending surgeons and residents, it follows a technique-based format and design that summarizes the surgical steps,from room set-up to closure, of all cases relevant to the 15 categories of "Orthopaedic Surgery Case Minimums" as determined by the ACGME." Provided by online publisher
"Assess and manage occlusion problems with confidence! Functional Occlusion in Restorative Dentistry and Prosthodontics provides a full-color, comprehensive guide to occlusion, with coverage ranging from an explanation of biological principles to treatment planning and clinical procedures. An easy-to-understand approach advances your skills with the latest evidence-based clinical research, and reinforces knowledge with chapter synopses, key points boxes, and abundant references. To support the book’s content, a companion website includes three video clips: condyle movements within the glenoid fossa, relationship between condylar translation and rotation, and movement of the condyle–disc assembly recorded by MRI. Edited by internationally renowned prosthodontics experts Iven Klineberg and Steven Eckert, this reference will help you treat occlusion conditions and TMJ disorders safely and effectively." Provided by online publisher
For decades, health care practitioners have relied on Middleton’s Allergy as their go-to reference for comprehensive information on allergic disorders. Now Middleton’s Allergy Essentials, by Drs. Robyn E. O'Hehir, Stephen T. Holgate, and Aziz Sheikh, offers a concise resource that’s both easily accessible and highly authoritative. Perfect for clinicians in primary and secondary care settings, this practical volume covers what is most useful in your daily practice, with a strong emphasis on disease diagnosis and management. Provided by online publisher
This book "encapsulates National Cancer Institute-collected evidence into a format that is optimally useful for hospital planners, physicians, researcher, and informaticians alike as they collectively strive to accelerate progress against cancer using informatics tools.
This book is a formational guide for turning clinical systems into engines of discovery as well as a translational guide for moving evidence into practice. It meets recommendations from the National Academies of Science to "reorient the research portfolio" toward providing greater "cognitive support for physicians, patients, and their caregivers" to "improve patient outcomes." Data from systems studies have suggested that oncology and primary care systems are prone to errors of omission, which can lead to fatal consequences downstream. By infusing the best science across disciplines, this book creates new environments of "Smart and Connected Health."
Oncology Informatics is also a policy guide in an era of extensive reform in healthcare settings, including new incentives for healthcare providers to demonstrate "meaningful use" of these technologies to improve system safety, engage patients, ensure continuity of care, enable population health, and protect privacy.Oncology Informatics acknowledges this extraordinary turn of events and offers practical guidance for meeting meaningful use requirements in the service of improved cancer care.
Anyone who wishes to take full advantage of the health information revolution in oncology to accelerate successes against cancer will find the information in this book valuable.
- Presents a pragmatic perspective for practitioners and allied health care professionals on how to implement Health I.T. solutions in a way that will minimize disruption while optimizing practice goals
- Proposes evidence-based guidelines for designers on how to create system interfaces that are easy to use, efficacious, and timesaving
- Offers insight for researchers into the ways in which informatics tools in oncology can be utilized to shorten the distance between discovery and practice" Provided by online publisher
This book "provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides for gene therapy.
The book explores the most recent developments in the field of polymer science and nanotechnology, and how these advancements have helped in the design of advanced materials. Non-viral vector systems, including cationic lipids, polymers, dendrimers, peptides and nanoparticles, are potential routes for compacting DNA for systemic delivery. However, unlike viral analogues that have no difficulty in overcoming cellular barriers and immune defense mechanisms, non-viral gene carriers consistently exhibit significant reduced transfection efficiency due to numerous extra- and intracellular obstacles. Therefore, biocompatibility and potential for large-scale production make these compounds increasingly attractive for gene therapy.
This book contains chapters on the engineering of polymers and nanomaterials for gene therapy, and how they can form complexes with DNA and avoid both in vitro and in vivo barriers. Other chapters describe in vitro, ex vivo, in vivo gene therapy studies, and the current issues affecting non-viral gene therapy.
- Explores current challenges in the research of genetic diseases
- Discusses polymers for gene therapy and their function in designing advanced materials
- Provides examples of organic and inorganic nanomaterials for gene therapy
- Includes labeling, targeting, and assays
- Looks at characterization, physico-(bio)chemical properties, and applications" Provided by online publisher
"The skin is the largest human organ system. Loss of skin integrity due to injury or illness results in a substantial physiologic imbalance and ultimately in severe disability or death. From burn victims to surgical scars and plastic surgery, the therapies resulting from skin tissue engineering and regenerative medicine are important to a broad spectrum of patients. Skin Tissue Engineering and Regenerative Medicine provides a translational link for biomedical researchers across fields to understand the inter-disciplinary approaches which expanded available therapies for patients and additional research collaboration. This work expands on the primary literature on the state of the art of cell therapies and biomaterials to review the most widely used surgical therapies for the specific clinical scenarios.- Explores cellular and molecular processes of wound healing, scar formation, and dermal repair
- Includes examples of animal models for wound healing and translation to the clinical world
- Presents the current state of, and clinical opportunities for, extracellular matrices, natural biomaterials, synthetic biomaterials, biologic skin substitutes, and adult and fetal stem and skin cells for skin regenerative therapies and wound management
- Discusses new innovative approaches for wound healing including skin bioprinting and directed cellular therapies" Provided by online publisher
This book "focuses on companies with technology development, offering inspiration, guidance, and hands-on advice on how to utilize the potential of a virtual company format.
The book provides an overview of key aspects of the company's activities, putting them into a comprehensive structure. In addition, both the rewards and risks of using the virtual company format are explored.
The virtual company format is here defined as a company with a small dedicated core staff. The company's development is performed by strategic alliances with external resource providers. In this way, the utilization of financial resources can be optimized with cost-effective product development. The book explores this concept and why it is attractive in a start-up phase for both companies who want to remain virtual and those that eventually want to develop into integrated traditional companies.
- Provides an overview, and understanding of, a virtual company's key activities
- Presents tactics that encourage communication between stakeholders associated with the virtual company
- Allows users to master all details, while managing key strategic issues
- Covers technology development and its required special skills and competencies" Provided by online publisher
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